Théa Pharma
Ophthalmology - Choroid
 
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subretinal granuloma

The peripheral retina appears detached through the presence of a thick choroidal fibrous scar with focal retinal pigment epithelium (RPE) proliferation. Subretinal granuloma occurs after a focal inflammation of the choroidal due principally to a toxocara canis infection. During the floride phase of inflammation, eosinophils and plasma cells are present. Then, proliferation and metaplasia of RPE occurs and, later, - as showed in this stereophotograph - extensive fibrosis of involved tissues form an inactive mass.

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Nevus of the choroid

A 2.32 mm elevated (basis:7.28mmx5.21mm) melanocytic choroidal nevus with serous detachament of the retina. Although the terminus nevus means a benign tumor, a nevus as seen in this picture must be closemeshedly monitored every 6 months because of the elevation, which is higher than 2 mm, and the presence of serous detachment of the retina. These secondary changes are suspicious of a malignant transformation. Other secondary changes can be observed, i.e. drusen and defects of the pigmented epithelium. Colour photography or better infrared photography- is essential for the clinical follow-up of choroidal nevi. Ultrasonography, fluorescein angiography as well as campimetry and laser-flare tyndallometry help to achieve correct evaluation of tumour progression. Choroidal nevi occur in about 20% of Caucasians and are very rarely observed in blacks.

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Department of Ophthalmology of the University Erlangen-Nürnberg, Germany
Edited by A. Bergua MD
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