Serpinginous choroiditis is an inflammation of unknown genesis affecting middle-aged patients between 30 an 50 years without sexual predilection. It has been described in association with HLA-B7. Serpinginous choroiditis is also know as a geographic helicoid peripapillary choroidopathy. It is always the case that both eyes are affected although with asymmetric intensity (one choroid is more affected than the other). The inflammation -with acute manifestation- begins peripapillary and extends centrifugally to the middle periphery of the fundus The macula could be affected by its expanding. The final stadium of the inflammation are hypo- and hyperpigmented scars of the choriocapillaris and the retinal pigment epithelium. Relapses originate from old scar borders. |